[CvGmt News] avviso Colloquio della Classe di Scienze prof. Jason Chin (19.06.2014) - reminder con abstract

valeria.giuliani at sns.it valeria.giuliani at sns.it
Thu Jun 12 11:47:09 CEST 2014



Da: valeria.giuliani at sns.it [mailto:valeria.giuliani at sns.it] 
Inviato: martedì 10 giugno 2014 09:33
A: 'docenti.scienze at sns.it'; 'ricercatori.scienze at sns.it'; Perfezionandi
Scienze; Studenti Scienze; borsisti.scienze at sns.it; Assegnisti Scienze;
'professoricontratto.scienze at sns.it'
Cc: 'Classi'; Sito SNS; Portineria Carovana; Alessandro Viegi; 'Valeria
Oggetto: avviso Colloquio della Classe di Scienze prof. Jason Chin


Colloqui Classe di Scienze


Giovedì 19 giugmo 2014

ore 15:00


Scuola Normale Superiore


(Sala Azzurra)


Jason Chin
Head, Centre for Chemical & Synthetic Biology

Programme Leader, Division of Protein & Nucleic Acid Chemistry, 

MRC Laboratory of Molecular Biology, Cambridge, UK



Terrà un seminario dal titolo:



“Reprogramming the Genetic Code”




The information for synthesizing the molecules that allow organisms to
survive and replicate is encoded in genomic DNA. In the cell, DNA is copied
to messenger RNA, and triplet codons (64) in the messenger RNA are decoded -
in the process of translation - to synthesize polymers of the natural 20
amino acids. This process (DNA RNA protein) describes the central dogma of
molecular biology and is conserved in terrestrial life. We are interested in
re-writing the central dogma to create organisms that synthesize proteins
containing unnatural amino acids and polymers composed of monomer building
blocks beyond the 20 natural amino acids. I will discuss our invention and
synthetic evolution of new 'orthogonal' translational components (including
ribosomes and aminoacyl-tRNA synthetases) to address the major challenges in
re-writing the central dogma of biology. I will discuss the application of
the approaches we have developed for incorporating unnatural amino acids
into proteins and investigating and synthetically controlling diverse
biological processes, with a particular emphasis on understanding the role
of post-translational modifications.




Tutti gli interessati sono invitati a partecipare.


Classe di Scienze




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