[CvGmt News] avviso Colloquio della Classe di Scienze prof.Michael Neuberger (16.03.2011)

[Valeria Giuliani]

Colloqui Classe di Scienze


Mercoledì 16 marzo 2011
ore 15.00

 

Scuola Normale Superiore

Pisa

(Sala Stemmi)



Michael Neuberger

MRC Laboratory of Molecular Biology

 

Terrà un seminario dal titolo:

 

"The Generation of Diversity in the Immune System"

 

Abstract:

 

Microbial infection has traditionally provided one of the greatest threats to human survival.  The immune system exists in order to combat such infection, but micro-organisms themselves mutate and evolve  to bypass immunity.  In order therefore to provide as broad a protection as possible, the immune system must generate an enormous diversity of weaponry (antibodies) to combat the vast array of micro-organisms.  Recent work has revealed that the immune system contains a specific  mutator protein whose job is to mutate the antibody genes themselves, allowing the generation of a vast array (> 1 billion) of antibodies from only a small number of antibody genes.  This targeted mutation also allows the antibodies themselves to change during the course of an infection, so that they adjust to the evolving pathogen. I will review what we have recently learned about how about how antibody diversity is generated through targeted mutation of DNA and consider how such information can be useful in medicine and biotechnology. 

 

Tutti gli interessati sono invitati a partecipare

 

Classe di Scienze

--------------------------------------------------------------------------------
Valeria Giuliani
Scuola Normale Superiore
Servizio Supporto Attività Didattiche - Scienze
Tel. 050-509260
Fax. 050-509045
Piazza dei Cavalieri, 7
56126 Pisa
E-Mail: v.giuliani at sns.it 
E-Mail: segreteria.scienze at sns.it

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